
Living with Migraine & Headache
Safe & Effective Relief

A migraine is a headache that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. Migraine attacks can last for hours to days, and the pain can be so severe that it interferes with your daily activities.
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For some people, a warning symptom known as an aura occurs before or with the headache. An aura can include visual disturbances, such as flashes of light or blind spots, or other disturbances, such as tingling on one side of the face or in an arm or leg and difficulty speaking.
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​After a migraine attack, you might feel drained, confused and washed out for up to a day. Some people report feeling elated. Sudden head movement might bring on the pain again briefly.

Migraine Causes and Triggers
Causes
Though migraine causes aren't fully understood, genetics and environmental factors appear to play a role. Changes in the brainstem and its interactions with the trigeminal nerve, a major pain pathway, might be involved. So might imbalances in brain chemicals — including serotonin, which helps regulate pain in your nervous system. Researchers are studying the role of serotonin in migraines. Other neurotransmitters play a role in the pain of migraine, including calcitonin gene-related peptide (CGRP).

Triggers
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There are a number of migraine triggers, including:
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Hormonal changes in women: Fluctuations in estrogen, such as before or during menstrual periods, pregnancy and menopause, seem to trigger headaches in many women.
Hormonal medications, such as oral contraceptives, also can worsen migraines. Some women, however, find that their migraines occur less often when taking these medications.
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Drinks: These include alcohol, especially wine, and too much caffeine, such as coffee.
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Stress: Stress at work or home can cause migraines.
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Sensory Stimuli: Bright or flashing lights can induce migraines, as can loud sounds. Strong smells — such as perfume, paint thinner, secondhand smoke and others — trigger migraines in some people.
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Sleep Changes: Missing sleep or getting too much sleep can trigger migraines in some people.
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Physical Factors: Intense physical exertion, including sexual activity, might provoke migraines.
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Weather Changes: A change of weather or barometric pressure can prompt a migraine.
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Medications: Oral contraceptives and vasodilators, such as nitroglycerin, can aggravate migraines.
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Foods: Aged cheeses and salty and processed foods might trigger migraines. So might skipping meals.
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Food Additives: These include the sweetener aspartame and the preservative monosodium glutamate (MSG), found in many foods.

A migraine is a headache that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. Migraine attacks can last for hours to days, and the pain can be so severe that it interferes with your daily activities.
​
For some people, a warning symptom known as an aura occurs before or with the headache. An aura can include visual disturbances, such as flashes of light or blind spots, or other disturbances, such as tingling on one side of the face or in an arm or leg and difficulty speaking.
​
After a migraine attack, you might feel drained, confused and washed out for up to a day. Some people report feeling elated. Sudden head movement might bring on the pain again briefly.
The Drug-Free Solution for Migraine and Cluster Headache
Treats and prevents migraine and cluster headache without pills, injections or drug like side effects.
GammaCore SapphireTM is the first and only FDA cleared non-invasive device to treat and prevent multiple types of headache pain via the vagus nerve. It’s small, handheld and portable for quick and easy treatments whenever and wherever needed.
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For acute use:
Treat right away and with a few 2-minute treatments, you could see fast acting, long-lasting pain relief.
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To prevent future headache pain:
Simply treat 3 times a day for more headache free days, so you can live life with less disruption.

Safe and well tolerated
Patients treated with gammaCore did not experience any serious treatment-related side effects. Most side effects are mild, occur during the use of the device, and go away quickly after each treatment.
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The most common side effects include discomfort and redness at the application site as well as dizziness. A tingling feeling where the device is applied is normal, but it should not cause major discomfort.

How gammaCore works
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gammaCore (nVNS) activates the vagus nerve with patented, gentle electrical stimulation.
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The vagus nerve is an important highway of communication between your brain and many parts of the body
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The vagus nerve plays an important role in regulating pain
Non-invasive vagus nerve stimulation with gammaCore is believed to help block the pain signals that cause migraines and cluster attacks.
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Unlike traditional vagus nerve stimulation therapies, gammaCore stimulates the nerve non-invasively through the skin without the need for surgery
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Avoids many drug-like side effects and inconveniences associated with injectable, inhaled, or pill-based medicines
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How to use gammaCore Sapphire


